At Curehub, your genetic blueprint is treated with the highest standard of scientific integrity and data privacy.
Trust Begins With Your DNA
Our Scientific Foundation
Backed by 10,000+ Peer-Reviewed Studies, and a globally recognized research team in epigenetics and gene editing.
Dr. Sándor Spisák
Chief Scientific Officer / Co-founder
Co-Founder · Chief Scientific Officer
Dr. Spisák is an internationally recognised molecular biologist specialising in epigenetics, gene regulation, functional genomics, and genome/epigenome editing.
He earned his PhD in Molecular Gastroenterology at Semmelweis University (Budapest), followed by:
- more than a decade of high-impact academic research in Boston,
including nearly 10 years at Harvard Medical School–affiliated institutes, most notably
the Dana-Farber Cancer Institute, where he worked as a postdoctoral researcher and later instructor.
Next to his involvment with Curehub he currently leads the Epigenetics & Genome Editing Research Group at HUN-REN TTK (Institute of Molecular Life Sciences), where his work focuses on uncovering the mechanistic foundations of epigenetic regulation and genetic variant function.
Academic & Scientific Highlights
Author of high-impact publications in Nature Medicine
→ CAUSEL methodology establishing causal links for non-coding GWAS variants
Read articlesPioneer of DNA-methylation–based liquid biopsy approaches
→ Demonstrated non-invasive molecular signal detection from blood and urine samples
Read articlesExtensive experience with genome & epigenome editing, single-cell technologies, and functional genomics
→ Systems-level analysis of epigenetic regulation and variant function
Read articlesRecipient of elite competitive research funding
→ MTA Bolyai János Research Fellowship
(nationally awarded on the basis of scientific excellence and independent research leadership)
(nationally awarded on the basis of scientific excellence and independent research leadership)
Focus of the Epigenetics & Genome Editing Research Group
Identifying which genetic variants are truly causal, especially within non-coding regulatory regions
Experimentally testing how variants alter biological regulation using genome and epigenome editing combined with cell-based functional assays
Building mechanistic, systems-level understanding of epigenetic regulation relevant to complex biological pathways and long-term physiological outcomes
Integrating computational biology and high-resolution experimental data to move beyond correlations toward validated biological logic
At Curehub
as Chief Scientific Officer,
he leads systems-level investigations into metabolism-linked epigenetic networks encompassing DNA, RNA, and histone methylation, and oversees high-throughput and targeted translational research programs.
This collaboration ensures that Curehub’s AI driven wellness insights are grounded in:
he leads systems-level investigations into metabolism-linked epigenetic networks encompassing DNA, RNA, and histone methylation, and oversees high-throughput and targeted translational research programs.
This collaboration ensures that Curehub’s AI driven wellness insights are grounded in:
Causally validated biological mechanisms, not statistical associations alone
Systems-level epigenetic thinking, aligned with real-world biology
Scientific rigor suitable for long-term platform credibility and regulatory awareness
Systems-level epigenetic thinking, aligned with real-world biology
Scientific rigor suitable for long-term platform credibility and regulatory awareness
Gene-Variant Informed Supplementation
Curehub’s foundation lies in analyzing genetic variants that influence human metabolism, with a particular focus on the One-Carbon Metabolism (OCM) pathway, which plays a central role in methylation processes, detoxification, and nutrient conversion.
By evaluating key SNPs (Single Nucleotide Polymorphisms) across genes such as MTHFR, COMT, MTR, MTRR, CBS, BHMT, and AHCY, the platform identifies potential functional bottlenecks within these pathways and translates them into personalized, actionable supplement recommendations with dosage guidance.
This science-driven approach forms the backbone of gene-variant–informed supplementation, enabling individualized health optimization strategies grounded in molecular biology and current scientific understanding.
By evaluating key SNPs (Single Nucleotide Polymorphisms) across genes such as MTHFR, COMT, MTR, MTRR, CBS, BHMT, and AHCY, the platform identifies potential functional bottlenecks within these pathways and translates them into personalized, actionable supplement recommendations with dosage guidance.
This science-driven approach forms the backbone of gene-variant–informed supplementation, enabling individualized health optimization strategies grounded in molecular biology and current scientific understanding.
Methylation Pathways and Epigenetic Precision
Methylation is a fundamental biochemical system involved in DNA repair, detoxification, and neurotransmitter balance.
Curehub’s AI model is informed by decades of methylation and epigenetic research, combining curated genetic rules, peer-reviewed scientific literature, and advanced AI synthesis to interpret relevant SNP patterns and translate them into personalized micronutrient recommendations with dosage guidance.
Through this approach, Curehub bridges the gap between genetic predisposition and functional insight, delivering research-grade epigenetic intelligence directly to the user in an accessible and actionable format.
Curehub’s AI model is informed by decades of methylation and epigenetic research, combining curated genetic rules, peer-reviewed scientific literature, and advanced AI synthesis to interpret relevant SNP patterns and translate them into personalized micronutrient recommendations with dosage guidance.
Through this approach, Curehub bridges the gap between genetic predisposition and functional insight, delivering research-grade epigenetic intelligence directly to the user in an accessible and actionable format.
Evidence-Backed Personalization
Every Curehub report and recommendation is informed by established scientific literature.
The platform references curated, peer-reviewed sources — including PubMed, SNPedia, and relevant clinical publications — to associate genetic variants with their documented biological roles and functional implications.
Through this evidence-informed approach, Curehub delivers personalized insights rather than generic suggestions, helping users better understand factors related to methylation efficiency, detoxification pathways, and metabolic function in a structured and actionable way.
The platform references curated, peer-reviewed sources — including PubMed, SNPedia, and relevant clinical publications — to associate genetic variants with their documented biological roles and functional implications.
Through this evidence-informed approach, Curehub delivers personalized insights rather than generic suggestions, helping users better understand factors related to methylation efficiency, detoxification pathways, and metabolic function in a structured and actionable way.
Your Privacy, Our Promise.
Your data is never sold,never shared, never compromised.
You're in control:delete your profile or data any time you'd like.
GDPR and HIPAA in practice:
End-to-End Encryption
Your DNA file is encrypted the moment you upload it, in transit and at rest.
Minimal Data Retention
We store only the data necessary for your analysis and apply strict data minimization practices. Data deletion is supported upon request.
No Selling, No Sharing
Your genetic and health data is never sold, rented, or shared with third parties.
Access Control
Access to your data is restricted to your authenticated account. Internal access is tightly controlled and logged under least-privilege policies.
Audit & Monitoring
All access and system activity is logged and monitored to support auditing and security reviews.
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Curehub Headquarters, Budapest, Hungary
(GMT+2) Time zone
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